May-Thurner syndrome is deep vein thrombosis of the iliofemoral vein. It is not a disease but a congenital anatomic variant. It is a genetic disorder that results from an abnormality of a chromosome. Chromosomes are thin strands of material found in the nucleus of each cell. They contain the genes that determine each person's characteristics. In may turner syndrome, one of the X chromosomes is missing or misshapen in most of the cells in the body. The reason for this total or partial loss of the chromosome usually cannot be found, but the loss occurs soon after the baby is conceived. There is nothing either parent can do to prevent this from happening; it is a biological accident for which no one is responsible. Girls with may turner syndrome are shorter than their peers and reach an average adult height of 4 feet 8 inches, although a few women may reach or exceed 5 feet in height. Their body proportions are normal. May turner syndrome is characterized by the presence of a single complete functioning sex-determining chromosome, the X chromosome, instead of two, either XX or XY. In may turner syndrome, female sexual characteristics are present but generally underdeveloped.

The most common features of may turner syndrome are short stature and reduced or absent development of the ovaries. As adults, women with this disorder are typically infertile. This condition occurs in about 1 in 2,500 female births worldwide, but is much more common among pregnancies that do not survive to term (miscarriages and stillbirths). Other complications of may turner syndrome include defects of the kidneys and heart, thyroid disease, arthritis and skeletal disorders, and development of type 2 diabetes. In early childhood, girls who have Turner syndrome may have frequent middle ear infections. Recurrent infections can lead to hearing loss in some cases. Girls with may turner Syndrome are usually of normal intelligence with good verbal skills and reading skills. Some girls, however, have problems with math, memory skills and fine-finger movements. People with may turner Syndrome are all different. Some may have many physical differences and symptoms, whereas others experience only a few medical problems. With early and appropriate medical care and ongoing support, most people with may turner Syndrome can lead normal, healthy, and productive lives.

Causes of May Thurner syndrome

Here are the list of the possible causes of May Thurner syndrome:

  • The exect cause or factors that put a couple at risk of having a daughter with may turner syndrome are not known.
  • An abnormality of a chromosome.

Symptoms of May Thurner syndrome

Some sign and Symptoms related to May Thurner syndrome:

  • Short stature.
  • Broad chest ( shield chest ) and widely-spaced nipples.
  • Low-set ears.
  • A webbed neck.
  • Drooping eyelids.
  • Hearing loss.
  • Pigmented moles.

Treatment of May Thurner syndrome

Some most common treatmet of May Thurner Syndrome:

  • Growth hormone may help a child with May turner syndrome grow taller.
  • Estrogen replacement therapy is often started when the girl is 12 or 13 years old. This helps trigger the growth of breasts, pubic hair, and other sexual characteristics.
  • Women with May turner syndrome who wish to become pregnant may consider using a donor egg.