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Polycythemia is a condition in which there is a net increase in the total number of red blood cells in the body. Polycythemia vera is a disorder of the blood-producing cells of the bone marrow that results in over production of red blood cells. PV may cause shortness of breath, dizziness, itchy or flushed skin, fatigue and headaches. The thickened blood flows more slowly through your small blood vessels and can form clots. PV tends to evolve into acute leukemia or a condition with the marrow replaced by scar tissue. Polycythemia vera is a relatively rare, chronic disorder characterized by an increase in red blood cell mass and in the concentration of hemoglobin. The increase in blood cells makes the blood more viscous, leading to strokes or tissue and organ damage. It is possible that the main title of the report Polycythemia Vera is not the name you expected. This is accompanied by increased white blood cell and platelet production, which is due to an abnormal clone of the hematopoietic stem cells with increased sensitivity to the different growth factors for maturation.

Polycythemia vera is a rare blood disorder in which there is an increase in all blood cells, particularly red blood cells. To have PV, there must be polycythemia which formally exists when the hemoglobin, red blood cell count, and total RBC volume are all above normal. Polycythemia vera is an abnormal increase in blood cells resulting from excess production by the bone marrow. Polycythemia vera is a clonal disorder arising in a multipotent hematopoietic progenitor cell that causes the accumulation of morphologically normal red cells, white cells, platelets, and their progenitors in the absence of a definable stimulus and to the exclusion of nonclonal hematopoiesis. This disease rarely occurs early in life. In polycythemia vera, the excess of red blood cells increases the volume of blood and makes it thicker, so that it flows less easily through small blood vessels. The overproduction of red blood cells may be due to a primary process in the bone marrow , or it may be a reaction to chronically low oxygen levels or, rarely, a malignancy . Polycythemia vera (PV) is a stem cell disorder characterized as a panhyperplastic, malignant, and neoplastic marrow disorder.

Causes of Polycythemia Vera

Common causes and risk factor's of Folic Acid Deficiency Anemia include the following : -

• The exact cause of polycythemia vera is unknown.

• White blood cells.
• Red blood cells.
• Platelets .
• Bone marrow.

Symptoms of Polycythemia Vera

Some of the common sign and symptoms of the disease Polycythemia Vera follows:

• Fatigue.
• Headache.
• Dizziness.
• Shortness of breath.
• Inability to concentrate.
• Night sweats.
• Flushed complexion.
• Bleeding gums.
• Hemoptysis.
• Iitchy skin.
• Numbness.
• High blood pressure.

Treatment of Polycythemia Vera

Find effective treatment methods of treating Polycythemia Vera :

• Certain medications, including chemotherapy.
• Phlebotomy - a procedure that involves removing blood from the body.
• Bone marrow transplantation.
• The goals of treating PV are to control your symptoms and reduce the risk of complications, especially stroke or heart attack , caused by thickened blood and blood clots